Welcome to the Tajerian Lab!

Research Areas

Below are some of the projects our lab has been working on. See anything you like? Get in touch to see how you can collaborate with our team or join our lab!

Neuronal traces.jpg

The extracellular interface of neuron-glia interactions

The brain extracellular matrix plays a key role in chronic pain. We examine the extracellular regulation of neuron-glia crosstalk, in vivo and in vitro, using various biophysical (AFM, SEM) and biochemical (IHC, single-cell western blotting) tools.

behavioral summary.jpg

Neurocognitive changes in chronic pain conditions

Pain is more than nociception. Experiencing chronic pain is often associated with alterations in mood and memory function. We study these changes in mice using complex behavioral paradigms.

Chronic Pain and autoimmunity

Chronic pain can involve autoimmune mechanisms as evidenced by auto-antibody deposition in central and peripheral tissues. We are currently studying the autoimmune contribution to pain-related brain plasticity using advanced biochemical tools.

 

Funding for Research and Training

We believe in providing the public with the sources for our lab funds. Below is the list of grants and awards that keep the Tajerian lab running. Travel awards, honoraria, and institutional start-up funds are not included.

  • Research grants

    1. Source of Funding: PSC-CUNY 62152-00 50

    Title of Project: The Hippocampal Extracellular Matrix Regulates Glia-Neuron Crosstalk

    Role on Project: PI

    Dates of Approved Project: 07/01/2019 – 06/30/2022

    2. Source of Funding: NIH 5SC2GM135114

    Title of Project: Hippocampal Extracellular Matrix Regulates Glia-Neuron Crosstalk after Injury

    Role on Project: PD/PI

    Dates of Approved Project: 09/10/2020 – 07/31/2023

    3. Source of Funding: PSC-CUNY 64724-00 52

    Title of Project: Circulating Autoantibodies Direct Autoimmune Mechanisms of Brain Plasticity in CRPS

    Role on Project: PI

    Dates of Approved Project: 07/01/2021 – 06/30/2023

    4. Source of Funding: Advanced Science Research Center Collaborative Seed Grant Program

    Title of Project: MALDI MS imaging in de-cellularized brain tissues: Technical advances and applications in the context of preclinical models of pathology

    Role on Project: PI

    Dates of Approved Project: 05/01/2024 – 08/31/2026

    5. Source of Funding: NIH R16NS140306

    Title of Project: Brain Vascular Plasticity in the Context of Peripheral Painful Trauma

    Role on Project: PI

    Dates of Approved Project: 04/01/2024-03/31/2028

    6. Source of Funding: Queens College Foundation Research Enhancement Award

    Title of Project: Development of a Multivariable Pain and Inflammation Testing Device for Mice

    Role on Project: PI

    Dates of Approved Project: 11/05/2024-05/31/2025

  • Training grants

    1. Source of Funding: NIH 5R25GM065096

    Title of Project: Queensborough Community College Bridges to the Baccalaureate Program

    Role on Project: Multiple PD/PI

    Dates of Approved Project: 09/01/2018 – 08/31/2023

    2. Source of Funding: NIH 5T34GM137858

    Title of Project: Bridges to the Baccalaureate Research Training Program at LaGuardia Community College

    Role on Project: Multiple PD/PI

    Dates of Approved Project: 08/01/2020 – 07/31/2025

    3. Source of Funding: NIH 1T34GM149475

    Title of Project: U-RISE at Queens College, CUNY

    Role on Project: Multiple PD/PI

    Dates of Approved Project: 04/2023 – 03/2028

  • Equipment grants

    1. Source of funding: CUNY Graduate Research Technology Initiative (GRTI)

    Title of Project: A Single-Cell Western Platform as part of an advanced proteomics workflow

    Role on Project: PI

    Dates of Approved Project: 10/01/2022 – 09/30/2023

    2.Source of Funding: NSF 2215946

    Title of Project:  MRI: Acquisition of a Zeiss LSM900 Confocal Microscope with Airyscan 2 to Accelerate Multidisciplinary Research and Training

    Role on Project: Senior Personnel   (PD/PI, Cathy Savage-Dunn)

    Dates of Approved Project:  10/01/2022 – 09/30/2025